Desbiens was the first female player drafted to the Quebec Junior AAA Hockey League, the second-highest men's junior league in Québec after the QMJHL. She was selected by the Loups de La Tuque but was cut before ever playing a game because the coach didn't believe there was any point in developing girls. That same year, she participated in the Shawinigan Cataractes training camp.  She made one playoff appearance for the Montréal Stars of the Canadian Women's Hockey League (CWHL) in 2012, as the team won the Clarkson Cup. 

In 2023, the PWHPA and the rival Premier Hockey Federation consolidated into the new Professional Women's Hockey League. With each of the six new teams able to make three initial free agency signings, Desbiens was widely assessed as a probable signing by the new PWHL Montreal. On September 5, she was reported as one of Montreal team's first three players, alongside Team Canada teammates Marie-Philip Poulin and Laura Stacey.

Desbiens was selected to play for Team Canada at the 2015 IIHF Women's World Championship, where she guided Canada to a silver medal. She was also selected to play for Team Canada at the 2018 Winter Olympics, where she again won a silver medal.